Yousuf Raza – Exploring the Oxymoron Wounded Healthcare

Yousuf Raza
AI: Summary ©
The conversation covers healthcare systems and mental health professional issues, including the need for policy research and education, the complex journey of medical college, and the importance of evidence-based medicine. The speakers emphasize the need for research and education to avoid double spending, the importance of avoiding double or triple spending, and the need for transparency and transparency in the industry. They also discuss the challenges of creating artificial drugs and the importance of marketing and advertising to encourage doctors to prescribe medications. The conversation ends with a brief advertisement for a teleaged session.
AI: Transcript ©
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Okay.

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everybody.

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This is Yusuf Raza and we are back

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with another episode of Psych.

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My apologies for not being able to do

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this the last time around.

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We had to delay this uh for um

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there there were certain personal issues that we

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had to attend to that I had to

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attend to.

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like we announced at the end of our

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previous episode and as was advertised as well,

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this month of the next 4 weeks or

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so, we're going to be talking about the

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wounded healthcare system, right?

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specifically, but also generally, doctor doctor

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is not the only part of the healthcare

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system.

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we would want for that to be as

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good as possible as convenient as possible and

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we were we are people we are the

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community that serves the larger health interests of

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the society or at at a to a

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very large extent corruption and other

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incredible.

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There's no other word to put it illnesses

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illnesses cancers that the healthcare system.

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they would.

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worsen the health of the society.

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hospitals.

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you're looking for an you're looking for a

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cure you're looking for better treatment better management,

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but if getting that treatment is complicated further

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if that complicates matters further for you.

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and is that even worth it for when

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that does come.

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Of course, that's that's one of the most

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important issues of our society.

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This is not to criticize any particular person

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or body or political institution or political party

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or anything like that this falls on all

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of us.

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I want to start by saying that there

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are problems.

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There are huge problems.

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And of course, there's a lot of good

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things as well.

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That's that's that's given we don't take that

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away.

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There's a lot of benefits a lot of

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good people a lot of good stuff coming

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out from the healthcare system as well, but

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precisely because it is the healthcare system.

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It is not good enough and there are

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some things which are so bad that it

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is embarrassing.

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It is flabbergasting as to how the providers

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of health are actually incredibly sick in so

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many ways and nobody's talking about those sicknesses.

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So we want to talk about those sicknesses.

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We want to talk about those sicknesses not

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with the intent to criticize not even with

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the intent to immediately have those sicknesses addressed.

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We'll get to realize the problems are so

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deep rooted and so prevalent and so global.

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It is preposterous to think that there can

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be any immediate solution for all of those

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problems, but precisely because they're so deep rooted.

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They're so deep seated.

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They're so prevalent.

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They're so global.

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We want the conversation to get started.

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Let's be honest, the conversation has gotten started,

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but it is not getting the requisite attention.

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There's people talking about it.

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There's journalists talking about it.

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There's doctors talking about it.

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There's a lot of people talking about it,

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but those people are not heard.

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A lot of what we say is not

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going to be heard immediately either, but we

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hope with your help, with our audience's help,

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we can reach the right corridors.

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We can reach the right people so that

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the conversation to fix this, to fix it,

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to improve situation as best as possible, the

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policies that need to be brought in, the

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changes that need to be brought in.

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What are those?

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Those conversations need to start.

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Predominantly, let's face it, when we talk about

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the illnesses of the healthcare system, there is

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one illness that trumps them all, and that

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is the big pharma.

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The involvement of pharmaceutical companies in our medical

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practice.

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There is good in it.

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Of course, there is.

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Good is not all that there is.

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There is some shocking level of bad and

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evil even that we want to bring our

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attentions to.

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For that reason, we have, and we did

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this before, I had a conversation on big

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pharma, and we realized there is so much

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more that is necessary.

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We are dedicating an entire month, and we

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brought together a team of very committed doctors

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to talk about this issue with us, to

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research this issue with us.

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I will quickly go ahead and introduce them

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to you.

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Foremost, we have Dr. Arooj Ramzan.

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Dr. Arooj Ramzan is a medical doctor, graduate

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of Rawalpindi Medical College, now at Rawalpindi Medical

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University, and she is also a mental health

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coach in telepsychiatry Pakistan with me.

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Thank you so much, Dr. Arooj, for being

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here.

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Assalamualaikum, sir.

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Thank you for inviting me over here.

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No problem at all.

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So moving right along, also a graduate of

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Rawalpindi Medical University, Dr. Asma Zia, I believe

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a batchmate of Dr. Arooj, and also with

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Dr. Arooj settled in Australia right now.

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She is a mental health ambassador for us

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at telepsychiatry Pakistan, one of the most committed

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researchers for our Big Pharma campaign, for our

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Wounded Healthcare campaign, excuse me.

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It was supposed to be the Big Pharma

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campaign, and we turned to realize that there's

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so much more than just Big Pharma here,

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but yeah.

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Thank you, Dr. Asma, for being here with

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us.

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You're most welcome, sir.

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Assalamualaikum.

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Walaikumassalam.

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And last but definitely not the least, Dr.

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Ghulam Murtaza, who is a graduate of University

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College Lahore.

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Did I get that right?

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That's it.

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And he's also a doctor and a prospective

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psychiatrist, one of the most committed and active

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researchers for this campaign, and an ambassador for

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telepsychiatry Pakistan.

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Thank you for being here.

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Okay.

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So, gee, before we get into the nuts

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and bolts, I want to ask, when all

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of you jumped on board and started working

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for this particular campaign and the research, the

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very meticulous research that all of you did,

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can you explain what you felt or the

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realizations that you came through?

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Let's start with Dr. It's very hard to

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explain it in a few lines, but I

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will try to summarize it and just, I

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won't say that it's a journey that started

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here.

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Basically, when we enter into the medical school,

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the background is that with the parents pressure,

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they come, some are for some particular monetary

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reasons, but there are some others, very few,

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who are coming into this profession because of

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the passion they had for human service.

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And I was one of them.

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I still try to be one of them.

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And medical college's journey is, due to our

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educational system, I would say complicated, you won't

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think about anything else.

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But once you get into the house job,

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and you think, now this is this, this

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is what I dreamt of my whole life,

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and you start working there, and you realize

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that this is not what I dreamt of.

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This is entirely different.

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There is service going on, but with that

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service, the trauma for the general public, the

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suffering for the general public, when you come

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to this school, you have to relieve people's

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suffering.

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And when your actions, or the system you

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are working in, because of that system, the

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suffering for the general public, then you can't

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be satisfied with yourself.

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You try to resist, you try to raise

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voice, but you are told that this has

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always been the case, so nothing can be

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done.

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Still, you try to take some steps, but

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you realize that this is a spider web.

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You can't do anything.

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There are people who are trying to do

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all that already, but still, even with their

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help, I was not able to do anything.

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There were times when I would come back,

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I had a call, and I would come

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back, and I was not able to sleep,

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because I knew that there was something, or

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there should be something, that we could have

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done for someone, but we were not doing

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that, not because we were not able to

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do that, but because the system was that.

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Now, after that, it was a long journey

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from the public system, I shifted to the

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private system for some time, and I thought

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that things would be better in the private

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system, there would be less rules and regulations,

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there would be less complicated mafias, which are

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of government servants, but I realized it's even

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a bigger spider web.

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There, the motto is, I'm not criticizing the

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private service, but for most of them, the

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motto is profit and waste lives, and that's

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how, I guess that is coming from the

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big pharma itself.

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The big pharma, which we are going to

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discuss today, you feel it the most there.

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I remember people who will be coming, who

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will be working with me, and who would

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be making double or triple amount of their

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salary, just because of the incentives to big

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pharma.

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So, who is paying for that?

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Public patient.

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So, it's a very complicated discussion.

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I will try to summarize it and present

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it in an easy way.

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The thing is, when I started working on

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this with our team, then I realized that

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what we have seen so far, that was

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just the tip of an iceberg.

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The things are so complicated.

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When I think about it, I guess that's

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a necessary side effect of this.

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I don't know what I'm going to do

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if any of us get sick in this

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health system, and are we ever going to

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trust it again or not.

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So, I guess things will get clear once

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we start discussing it, but all of us

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will realize that things are so deep-rooted,

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and I realized this, like you said, that

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whenever we are researching a topic, we will

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find a solution for it, but there was

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not any solution or a single solution for

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it.

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So, I realized that if we want to

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do something for it, the first step would

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be to raise awareness, that the public should

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know about it.

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Once they know about it, then we might

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be able to do something.

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Thank you.

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Thank you for sharing all of that.

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Just a couple of things.

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As medical students, as doctors, all of us

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experience that.

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To retain that sensitivity, somewhere along the way,

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it's lost.

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Somewhere along the way, that sensitivity, that concern,

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that care is lost.

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Our selfish interests take precedence.

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And then we realize that if we want

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to survive in this system, then we have

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to do the same.

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And we have to remain silent.

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Let what is happening happen.

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Don't let what is right happen.

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Do your part and go home to your

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family.

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So, it's kudos to you to be able

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to retain that sensitivity and still be here.

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Thank you for sharing that.

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Dr. Asma, sentiments, feelings, going through this, all

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that research that you did.

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Paranoia.

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I'm like, now that I'm not there in

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person, I'm like, it is,

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it's a shame that you can't trust them.

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And, after that, overall, our perception is that

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doctors are the ones that are responsible.

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Because they are at the front of healthcare.

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Your nurses are there.

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So, all the blame, all the policies, all

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the working, the public doesn't know that.

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They see the doctors.

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That also is the fault of doctors.

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So, I think this campaign is going to

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bring a lot of knowledge to the common

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man.

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Because every time a scandal comes up, So,

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I think this campaign will help in bringing

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up a better understanding, proper, big picture.

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So, they can properly identify that this person

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or this entity is responsible.

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It's not always the doctors.

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Sometimes, yes, doctors are the ones that are

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responsible, but not always.

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So, I think this is what I'm hoping

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to achieve.

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Great.

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Thank you.

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Thank you so much.

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And I'm completely on board with you.

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The paranoia that coming to know all of

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these truths, these facts, that what's going on,

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how dirty it is, then it's clear.

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That trust, leaving, getting up, and let's be

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clear, we're very aware that by putting this

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kind of awareness in the public, and by

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talking so openly about these things, we may

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be creating these negative sentiments in people.

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That if we don't go to the doctor,

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where do we go when we get sick?

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Where are we going to go?

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At the end of the day, that's the

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only option we do have.

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All the more reason that this is important.

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See, what the Zainab incident did for child

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sexual abuse, these things have always been happening,

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and are still happening, but at least, after

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getting so much public attention, something or the

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other happened.

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Somehow or the other, people started taking preventive

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measures, there was a movement in the media,

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in the political circles, you know, the motorway

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incident, it had a similar effect.

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The trust that people have for police, or

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the lack thereof, all that came out.

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But towards a particular end, something needs to

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be done.

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Things are not okay the way they are.

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So yes, the side effect of our raising

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awareness may be that people start becoming paranoid.

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We are aware of that side effect, but

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the situation is such that we have to

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take that risk.

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We have to go ahead and open these

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Pandora's boxes, to see if in the long

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run, some good can come out of it.

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It's about time.

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It's about time.

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Thank you.

00:18:46 --> 00:18:47

Thank you, Dr. Asma.

00:18:48 --> 00:18:51

Dr. Ghulam Murtaza, how was your experience finding

00:18:51 --> 00:18:54

out all that you found out?

00:18:56 --> 00:18:58

I think we're very aware of all these

00:18:58 --> 00:19:02

problems while working, especially during house job.

00:19:03 --> 00:19:06

But going through the data, when you're faced

00:19:06 --> 00:19:08

with actual evidence, it hits you differently.

00:19:10 --> 00:19:13

And the other thing is, we're not always

00:19:13 --> 00:19:14

doctors.

00:19:14 --> 00:19:15

We get sick as well.

00:19:16 --> 00:19:20

Sometimes our loved ones get sick, and then

00:19:20 --> 00:19:22

you're on the other end.

00:19:22 --> 00:19:26

That's when these problems come to light in

00:19:26 --> 00:19:28

a very real way for you.

00:19:28 --> 00:19:31

Because now you're on the opposite end.

00:19:31 --> 00:19:32

You're on the receiving end of it.

00:19:33 --> 00:19:37

I think going through the data, it wasn't

00:19:37 --> 00:19:38

shocking.

00:19:39 --> 00:19:43

It was basically things that we're very aware

00:19:43 --> 00:19:48

of, but seeing the data, it just had

00:19:48 --> 00:19:50

a completely different effect on me.

00:19:50 --> 00:19:53

Some of it was really depressing.

00:19:53 --> 00:19:57

I think we talked about it with Dr.

00:19:57 --> 00:19:58

Asma and Dr. Arooj.

00:20:00 --> 00:20:03

We started feeling negative about our own professions.

00:20:05 --> 00:20:10

The other thing is, there's a pandemic going

00:20:10 --> 00:20:14

on, and doctors are fighting against COVID.

00:20:14 --> 00:20:16

Some are losing their lives.

00:20:17 --> 00:20:22

We did not want a negative stigma against

00:20:22 --> 00:20:23

doctors to grow.

00:20:23 --> 00:20:26

We wanted instead to start these conversations.

00:20:27 --> 00:20:30

Our intention is not to chastise anyone.

00:20:30 --> 00:20:33

We just want to explore these issues, and

00:20:33 --> 00:20:34

I think it's about time.

00:20:36 --> 00:20:38

One of the reasons why I asked this

00:20:38 --> 00:20:40

question, or why I started off this question,

00:20:40 --> 00:20:42

when we were having internal meetings and discussions,

00:20:42 --> 00:20:46

I remember Dr. Murtaza making this comment before

00:20:46 --> 00:20:48

he started his presentation.

00:20:52 --> 00:20:56

Because we share that sentiment, I felt bringing

00:20:56 --> 00:20:58

some of that out is called for.

00:20:59 --> 00:21:00

Let's dive straight in.

00:21:02 --> 00:21:04

I'll start with Dr. Murtaza.

00:21:13 --> 00:21:18

What is polypharmacy?

00:21:18 --> 00:21:19

What is polypharmacy?

00:21:20 --> 00:21:24

Why is it so prevalent?

00:21:26 --> 00:21:32

First of all, polypharmacy is basically long prescriptions,

00:21:34 --> 00:21:38

exceeding 5 medications on a daily basis.

00:21:38 --> 00:21:39

5 different medications.

00:21:39 --> 00:21:44

So, it's becoming really common, and it's such

00:21:44 --> 00:21:47

a burden on patients, it's such a burden

00:21:47 --> 00:21:49

on our healthcare system.

00:21:50 --> 00:21:52

A long list of medications is written.

00:21:52 --> 00:21:54

One is not readable.

00:21:55 --> 00:21:56

It's difficult to understand.

00:21:58 --> 00:22:00

Finding them is difficult.

00:22:00 --> 00:22:02

You go to the pharmacist.

00:22:02 --> 00:22:04

One medication's name is something else.

00:22:05 --> 00:22:06

You're basically confused.

00:22:06 --> 00:22:09

As a layperson, you have no idea what

00:22:09 --> 00:22:09

to do.

00:22:10 --> 00:22:12

Then you have to remember when to take

00:22:12 --> 00:22:16

it, where to take it, all its costs,

00:22:16 --> 00:22:19

and that contributes to a thing called pill

00:22:19 --> 00:22:20

burden.

00:22:21 --> 00:22:23

That's why you give up, and you don't

00:22:23 --> 00:22:24

take medications altogether.

00:22:28 --> 00:22:32

Polypharmacy is very prevalent, and there are some

00:22:32 --> 00:22:35

legitimate reasons for it.

00:22:36 --> 00:22:39

Number one, it's possible that someone has multiple

00:22:39 --> 00:22:40

diseases.

00:22:41 --> 00:22:42

One medication won't work.

00:22:43 --> 00:22:47

Second, this is a worldwide problem that our

00:22:47 --> 00:22:51

elderly population, as a proportion, is increasing.

00:22:51 --> 00:22:54

As age increases, diseases also increase.

00:22:56 --> 00:22:58

Long-term medicines also have to increase.

00:22:59 --> 00:23:02

So, those are some of the basic reasons.

00:23:03 --> 00:23:06

In our setup, if you go to a

00:23:06 --> 00:23:10

doctor and they tell you to lose weight,

00:23:10 --> 00:23:15

to exercise, they'd be like, we don't need

00:23:15 --> 00:23:16

you to tell us this.

00:23:16 --> 00:23:17

We know this.

00:23:19 --> 00:23:24

They expect you to get quick relief, which

00:23:24 --> 00:23:26

makes sense from their point of view, obviously.

00:23:28 --> 00:23:32

As a result, doctors have to prescribe excessive

00:23:32 --> 00:23:33

medications.

00:23:34 --> 00:23:37

One reason is that we treat symptoms.

00:23:39 --> 00:23:42

We don't try to find cures.

00:23:43 --> 00:23:46

Similarly, the list of medicines keeps increasing.

00:23:47 --> 00:23:51

On the shadier side of things, which is

00:23:51 --> 00:23:54

our main focus, I guess, big pharma plays

00:23:54 --> 00:23:54

a role.

00:23:55 --> 00:24:01

They're always offering incentives and this occurs at

00:24:01 --> 00:24:02

every level.

00:24:03 --> 00:24:06

It starts at the clinical trial level, at

00:24:06 --> 00:24:13

the decision-making level, that will we lose

00:24:13 --> 00:24:14

customers?

00:24:14 --> 00:24:16

Will we lose lifelong customers?

00:24:16 --> 00:24:18

That's the sort of thinking.

00:24:19 --> 00:24:24

Because before ethics, financial considerations come up.

00:24:24 --> 00:24:28

So, there's a problem with decision-making.

00:24:29 --> 00:24:33

After that, clinical trials at every level have

00:24:33 --> 00:24:34

big pharma's influence.

00:24:36 --> 00:24:39

They hide some of the side effects over

00:24:39 --> 00:24:43

a period of years and what that results

00:24:43 --> 00:24:44

in.

00:24:44 --> 00:24:46

Then they promote these drugs to doctors.

00:24:47 --> 00:24:50

Obviously, we're not aware of all.

00:24:50 --> 00:24:53

We're only as good as our information.

00:24:53 --> 00:24:56

So, what happens is that we start prescribing

00:24:56 --> 00:24:59

those medications without a very good idea of

00:24:59 --> 00:25:03

certain side effects, without a good idea of

00:25:03 --> 00:25:05

drug interactions, for example.

00:25:06 --> 00:25:06

So, that's what happens.

00:25:07 --> 00:25:08

This problem keeps increasing.

00:25:09 --> 00:25:12

Lists keep getting longer and it becomes a

00:25:12 --> 00:25:12

torture for the patient.

00:25:15 --> 00:25:18

Thank you for clarifying that, Dr. Murtaza.

00:25:18 --> 00:25:22

Dr. Murtaza, when I and Azam had a

00:25:22 --> 00:25:29

meeting, we spoke about how polypharmacy, especially in

00:25:29 --> 00:25:35

psychiatry or in any other field, patients don't

00:25:35 --> 00:25:38

even realize which medication is for whom.

00:25:39 --> 00:25:42

Which is a necessary medication.

00:25:42 --> 00:25:44

When you prescribe 5, 6, 7, 8 medications,

00:25:45 --> 00:25:48

one or two of them are genuinely life

00:25:48 --> 00:25:49

-saving.

00:25:50 --> 00:25:53

They keep the disease in mind and are

00:25:53 --> 00:25:54

necessary for the patient's life.

00:25:55 --> 00:25:59

But when they become 7 or 8, then

00:25:59 --> 00:26:02

which one is just a useless vitamin which

00:26:02 --> 00:26:04

is not even needed, which is often not

00:26:04 --> 00:26:04

needed.

00:26:05 --> 00:26:08

And which is a medication to keep your

00:26:08 --> 00:26:12

blood pressure down, which is a medication to

00:26:12 --> 00:26:12

keep your blood pressure under control.

00:26:13 --> 00:26:15

The patients have no clue.

00:26:17 --> 00:26:22

For them, each medicine is equally important or

00:26:22 --> 00:26:23

equally unimportant.

00:26:24 --> 00:26:27

Like you said, the pill burden, what it

00:26:27 --> 00:26:27

does to them.

00:26:29 --> 00:26:33

And I can say for psychiatry, for most

00:26:34 --> 00:26:39

psychological problems, even a diagnosis is not necessary.

00:26:40 --> 00:26:41

Most psychological problems.

00:26:42 --> 00:26:47

For most psychiatric diagnoses, which are not more

00:26:47 --> 00:26:51

than mild severity, medications are usually not necessary

00:26:51 --> 00:26:53

and should not be recommended.

00:26:55 --> 00:27:00

In the moderate and severe category, psychiatric illnesses,

00:27:00 --> 00:27:08

even there, one or two medications are most

00:27:08 --> 00:27:14

usually recommended in the most severe of illnesses.

00:27:15 --> 00:27:16

Even if not two, go for three.

00:27:18 --> 00:27:20

Most severe of conditions.

00:27:22 --> 00:27:29

But where there is resistance, no response, understandable.

00:27:30 --> 00:27:36

But even then, the situation doesn't call for

00:27:36 --> 00:27:39

seven or eight medications.

00:27:39 --> 00:27:40

Five or six.

00:27:42 --> 00:27:46

What happens even in mild illnesses?

00:27:49 --> 00:27:50

Forget about illnesses.

00:27:51 --> 00:27:54

Psychological problems and challenges that don't even warrant

00:27:54 --> 00:27:55

a diagnosis.

00:27:56 --> 00:27:57

Medications are far-fetched.

00:27:57 --> 00:28:00

Even mild illnesses are far-fetched.

00:28:01 --> 00:28:05

In them, five or six medications are given.

00:28:07 --> 00:28:11

That is downright corruption at the part of

00:28:11 --> 00:28:12

the psychiatrist.

00:28:15 --> 00:28:16

That's pure evil.

00:28:17 --> 00:28:19

There's no other way of looking at it.

00:28:20 --> 00:28:21

And it's there, it's happening.

00:28:22 --> 00:28:23

People do that.

00:28:24 --> 00:28:27

And they call themselves psychiatrists, they call themselves

00:28:27 --> 00:28:27

humans.

00:28:28 --> 00:28:31

They have their justifications, but it's...

00:28:31 --> 00:28:33

This is how bad it gets.

00:28:33 --> 00:28:43

And then we say that these recommendations are...

00:28:43 --> 00:28:47

How do doctors distinguish themselves?

00:28:47 --> 00:28:51

Doctors distinguish themselves from Desi Totke on the

00:28:51 --> 00:28:53

basis of evidence.

00:28:54 --> 00:28:57

That we practice evidence-based practice.

00:28:58 --> 00:29:01

And this is our...

00:29:02 --> 00:29:06

Coming from that field, knowing that evidence, I

00:29:06 --> 00:29:08

know that the practice that is going on

00:29:08 --> 00:29:09

is not evidence-based.

00:29:10 --> 00:29:13

The evidence does not say write eight medications

00:29:13 --> 00:29:14

or nine medications for something that doesn't even

00:29:14 --> 00:29:15

warrant a diagnosis.

00:29:16 --> 00:29:17

The evidence does not say that.

00:29:17 --> 00:29:19

But having said that, what is this evidence

00:29:19 --> 00:29:21

-based medicine, Dr. Murtaza?

00:29:23 --> 00:29:24

It's this idea...

00:29:24 --> 00:29:28

We've sort of garbed modern medicine around this

00:29:28 --> 00:29:32

idea that doctors are clinical scientists by definition.

00:29:33 --> 00:29:35

And as a scientist, you're only as good

00:29:35 --> 00:29:36

as your information.

00:29:37 --> 00:29:42

So that evidence includes clinical trials, it includes

00:29:42 --> 00:29:47

our personal experiences, it includes patient data and

00:29:47 --> 00:29:47

references.

00:29:48 --> 00:29:52

That's so-called EBM, evidence-based medicine.

00:29:53 --> 00:30:00

But having delved into Big Pharma's influence, we're

00:30:00 --> 00:30:05

starting to doubt the validity of such evidence.

00:30:07 --> 00:30:09

Because it starts from the higher levels or

00:30:09 --> 00:30:12

publications, promotions.

00:30:13 --> 00:30:15

A lot of it is in their hands

00:30:15 --> 00:30:17

and it should not be the case.

00:30:18 --> 00:30:24

And so many bogus studies are published every

00:30:24 --> 00:30:27

year and it's become...

00:30:27 --> 00:30:30

When it enters the pool of knowledge, that's

00:30:30 --> 00:30:34

when patients suffer a loss because we're going

00:30:34 --> 00:30:34

in blind.

00:30:37 --> 00:30:39

Okay, so there is evidence that evidence-based

00:30:39 --> 00:30:41

medicine is not based on evidence.

00:30:42 --> 00:30:44

Can we say that?

00:30:46 --> 00:30:47

Oh boy.

00:30:47 --> 00:30:52

So moving right along from here, we talked

00:30:52 --> 00:30:57

about pharmaceutical companies, influencing the evidence-based medicine,

00:30:57 --> 00:31:01

influencing the research and what affects it.

00:31:03 --> 00:31:11

We thought that pharmaceutical companies' investment is in

00:31:11 --> 00:31:18

creating genuine evidence so that people's lives can

00:31:18 --> 00:31:18

be saved.

00:31:19 --> 00:31:21

Dr. Arooj, is that the case?

00:31:21 --> 00:31:23

Is that always the case?

00:31:24 --> 00:31:24

Unfortunately.

00:31:25 --> 00:31:26

Unfortunately, no.

00:31:27 --> 00:31:28

I used to feel the same.

00:31:28 --> 00:31:30

I guess all of us team members felt

00:31:30 --> 00:31:30

the same.

00:31:31 --> 00:31:34

We were very, very particular about this evidence

00:31:34 --> 00:31:36

-based medicine, about all the researches that are

00:31:36 --> 00:31:37

coming.

00:31:38 --> 00:31:40

But when we looked at it in detail,

00:31:41 --> 00:31:45

when we went into this web, we realized

00:31:45 --> 00:31:48

that the pharmaceutical companies' approach is not limited

00:31:48 --> 00:31:48

to doctors.

00:31:48 --> 00:31:53

It's not limited to pharmaceutical products.

00:31:54 --> 00:31:57

It's not limited to evidence-based medicine, research,

00:31:57 --> 00:32:00

and the decision about what kind of medicine

00:32:00 --> 00:32:02

to make and what not to make.

00:32:03 --> 00:32:05

It's their decision now.

00:32:06 --> 00:32:13

Usually, it's predicted that if a type of

00:32:13 --> 00:32:16

disease is becoming prevalent or if the death

00:32:16 --> 00:32:21

ratio is high, pharmaceutical companies should invest more

00:32:21 --> 00:32:24

in it, research it, and make medicines.

00:32:25 --> 00:32:28

But when there is a lot of scientific

00:32:28 --> 00:32:35

evidence which scientifically proves that, let's suppose, in

00:32:35 --> 00:32:36

this time, we take antibiotics.

00:32:38 --> 00:32:42

Antibiotics, although infections are not as common as

00:32:42 --> 00:32:44

they used to be, but when they do

00:32:44 --> 00:32:47

happen, they are as severe as they used

00:32:47 --> 00:32:47

to be.

00:32:48 --> 00:32:50

And the death rate increases.

00:32:51 --> 00:32:54

There is a research study which says that

00:32:54 --> 00:32:59

7 million people these days, 7 million people

00:32:59 --> 00:33:02

every year die due to some infectious cause

00:33:02 --> 00:33:05

which can be treatable if we have a

00:33:05 --> 00:33:06

drug for it.

00:33:06 --> 00:33:10

This is predicted that by 2050, it will

00:33:10 --> 00:33:10

be 10 million.

00:33:11 --> 00:33:15

But this is a data which tells us

00:33:15 --> 00:33:17

how prevalent this disease is.

00:33:18 --> 00:33:22

In comparison, we were expecting that pharmaceutical companies

00:33:22 --> 00:33:24

should do research on these medicines, on the

00:33:24 --> 00:33:29

drug resistance and to tackle all these infections,

00:33:30 --> 00:33:35

they should make new antibiotics which will target

00:33:35 --> 00:33:37

all the viruses and bacteria.

00:33:37 --> 00:33:41

But when you look at it, the pharmaceutical

00:33:41 --> 00:33:45

companies made the antibiotics in the 1980s.

00:33:46 --> 00:33:49

After that, if you look at it, there

00:33:49 --> 00:33:51

are no new antibiotics.

00:33:51 --> 00:33:54

There are the same types and modifications but

00:33:54 --> 00:33:57

no new antibiotics because they have reduced the

00:33:57 --> 00:33:58

research on it.

00:33:59 --> 00:34:01

Ultimately, it is predicted that they are going

00:34:01 --> 00:34:02

to stop.

00:34:02 --> 00:34:05

But now, if we compare it with the

00:34:05 --> 00:34:07

disease ratio, it has reduced a lot.

00:34:08 --> 00:34:08

What is the reason?

00:34:10 --> 00:34:13

This concept that you have to take a

00:34:13 --> 00:34:17

pill every day and that will be the

00:34:17 --> 00:34:19

most beneficial for the pharma profit.

00:34:20 --> 00:34:21

But when you take an antibiotic for an

00:34:21 --> 00:34:24

infection, for how many days?

00:34:25 --> 00:34:27

Usually, it is 5-10 days.

00:34:27 --> 00:34:29

If there is a lot of resistance we

00:34:29 --> 00:34:31

go for 14 days.

00:34:31 --> 00:34:33

This is an antibiotic made by the pharma

00:34:33 --> 00:34:36

company which the patient will take for 14

00:34:36 --> 00:34:37

days and that's it.

00:34:38 --> 00:34:41

Let's suppose if you cure it well and

00:34:41 --> 00:34:44

remove all the hygienic measures, then ultimately the

00:34:44 --> 00:34:45

infection rate will reduce.

00:34:46 --> 00:34:50

But when you go towards blood pressure medications,

00:34:51 --> 00:34:57

cholesterol blocker medications, birth control pills, although these

00:34:57 --> 00:35:02

are prevalent diseases in this time, but not

00:35:02 --> 00:35:03

as rare as antibiotics.

00:35:04 --> 00:35:07

Pharmaceutical companies are investing in this direction.

00:35:08 --> 00:35:08

Why?

00:35:08 --> 00:35:10

Because patients will take that pill for the

00:35:10 --> 00:35:11

rest of their lives.

00:35:12 --> 00:35:13

Where they get a profit of 14 days,

00:35:14 --> 00:35:15

they will get a profit of 20, 30,

00:35:16 --> 00:35:16

40 years.

00:35:18 --> 00:35:21

There are some sayings by pharmaceutical companies, CEOs,

00:35:21 --> 00:35:23

and managers which say that antibiotics are not

00:35:23 --> 00:35:24

a profitable business.

00:35:25 --> 00:35:25

So, for whom is it not a profitable

00:35:25 --> 00:35:26

business?

00:35:26 --> 00:35:27

For the pharma.

00:35:27 --> 00:35:29

But who has to suffer?

00:35:29 --> 00:35:30

Patients.

00:35:30 --> 00:35:34

So, when you analyze this in different aspects,

00:35:35 --> 00:35:38

then you realize that big pharma has a

00:35:38 --> 00:35:40

motto that is profit vs lives.

00:35:41 --> 00:35:46

Initially, they used to do all those researches

00:35:46 --> 00:35:50

and clinical trials for the purpose of saving

00:35:50 --> 00:35:50

lives.

00:35:51 --> 00:35:53

But now when you see this trend, it's

00:35:53 --> 00:35:53

just profit.

00:35:53 --> 00:35:57

There is no public service or there is

00:35:57 --> 00:35:59

nothing going on for the sake of patients.

00:36:23 --> 00:36:24

I should make that.

00:36:24 --> 00:36:27

And that makes good business sense.

00:36:28 --> 00:36:29

Right?

00:36:30 --> 00:36:33

Wedding dresses have to be really expensive just

00:36:33 --> 00:36:33

to justify.

00:36:33 --> 00:36:35

Because sales come in.

00:36:38 --> 00:36:41

And whether it's a wedding dress or any

00:36:41 --> 00:36:44

other dress or medicines, it's the same thing,

00:36:44 --> 00:36:44

right?

00:36:45 --> 00:36:45

This is the problem.

00:36:47 --> 00:36:49

Sir, why do you think that this is

00:36:49 --> 00:36:50

a lawn branch?

00:36:50 --> 00:36:50

Why is it a lawn branch?

00:36:53 --> 00:36:55

The problem is this.

00:36:55 --> 00:36:58

We started running our healthcare on a business

00:36:58 --> 00:36:58

model.

00:37:00 --> 00:37:01

And that's where the problem actually started.

00:37:02 --> 00:37:03

Okay.

00:37:03 --> 00:37:07

So, now we are getting to see this.

00:37:08 --> 00:37:15

Our healthcare system for us to provide effective,

00:37:15 --> 00:37:24

efficient healthcare system models from economics and models

00:37:25 --> 00:37:31

dealing with economic theories are more relevant to

00:37:31 --> 00:37:33

us than we were given to understand.

00:37:36 --> 00:37:43

What economic models or what theories underpin the

00:37:43 --> 00:37:48

business models that are driving the pharmaceutical industries

00:37:49 --> 00:37:51

and how deeply tied in that is with

00:37:51 --> 00:37:52

us.

00:37:53 --> 00:37:54

But we don't want to study anything other

00:37:54 --> 00:37:56

than anatomy, physiology and biochemistry.

00:37:57 --> 00:37:59

What do we care about economics?

00:37:59 --> 00:38:01

What do we care about all those fields?

00:38:03 --> 00:38:05

But they're doing what they're doing to us.

00:38:06 --> 00:38:09

As a result, our ignorance continues.

00:38:10 --> 00:38:11

Okay.

00:38:11 --> 00:38:15

So, this big pharma, is it only limited

00:38:15 --> 00:38:16

to these medications?

00:38:17 --> 00:38:23

Life-saving or continuously is that all there

00:38:23 --> 00:38:23

is?

00:38:23 --> 00:38:28

Or do they influence their involvement beyond that

00:38:28 --> 00:38:29

in any way?

00:38:30 --> 00:38:31

Yes, definitely.

00:38:32 --> 00:38:35

That's, I guess, the other half of this

00:38:35 --> 00:38:35

big problem.

00:38:37 --> 00:38:40

Dr. Murtaza basically did an evidence-based medicine,

00:38:40 --> 00:38:46

which we practice and it's like a sacred

00:38:46 --> 00:38:47

holy thing for us doctors.

00:38:48 --> 00:38:52

But when we start studying about it, where

00:38:52 --> 00:38:54

does a disease come from?

00:38:55 --> 00:38:57

When research is done on it, it is

00:38:57 --> 00:38:58

considered a disease.

00:38:58 --> 00:39:00

Medicines are prescribed for it.

00:39:00 --> 00:39:02

Ideally, who should have done all this work?

00:39:02 --> 00:39:07

Healthcare body, doctors, a medical experts team.

00:39:07 --> 00:39:10

But when we see some diseases which are

00:39:10 --> 00:39:13

becoming very common and almost everyone knows that

00:39:13 --> 00:39:14

this is inside me.

00:39:14 --> 00:39:16

Dr. Google has told them that this is

00:39:16 --> 00:39:16

inside me.

00:39:17 --> 00:39:19

When we see where they have come from,

00:39:19 --> 00:39:24

then we realize that behind that, behind introducing

00:39:24 --> 00:39:26

that disease, big pharma has played a very

00:39:26 --> 00:39:27

big role.

00:39:28 --> 00:39:34

Let's suppose, this concept is called disease bongering

00:39:34 --> 00:39:37

or medicalization and when we started doing research

00:39:37 --> 00:39:40

on it, we thought no one would know

00:39:40 --> 00:39:41

this much and we wouldn't have much data

00:39:41 --> 00:39:42

on it.

00:39:43 --> 00:39:45

But there is a whole book written on

00:39:45 --> 00:39:46

it in 1992.

00:39:47 --> 00:39:49

At that time, a whole book was written

00:39:49 --> 00:39:51

on it by a scientific writer, his name

00:39:51 --> 00:39:53

was Len Pair and he introduced this concept.

00:39:54 --> 00:39:56

Now it is 1992 and today it is

00:39:56 --> 00:39:58

2021 so you can imagine to what extent

00:39:58 --> 00:40:01

this concept would have become prevalent.

00:40:02 --> 00:40:04

So what happens is, I will explain this

00:40:04 --> 00:40:05

with an example.

00:40:06 --> 00:40:10

Let's suppose, in 1980s, a pharmaceutical company made

00:40:10 --> 00:40:13

a drug which is called paroxetine and they

00:40:13 --> 00:40:16

saw that people who have social anxiety, when

00:40:16 --> 00:40:18

you go to a public gathering, you start

00:40:18 --> 00:40:21

talking and you get a little shyness, this

00:40:21 --> 00:40:23

paroxetine controls that anxiety.

00:40:24 --> 00:40:26

So they introduced this drug for social phobia.

00:40:27 --> 00:40:28

Now that's a good thing because social phobia

00:40:28 --> 00:40:30

is a genuine problem.

00:40:31 --> 00:40:33

Some people have it to a very severe

00:40:33 --> 00:40:35

extent where we can't consider it normal.

00:40:36 --> 00:40:39

But that ratio of people was very low.

00:40:40 --> 00:40:43

Now, what did they do to promote this

00:40:43 --> 00:40:43

drug?

00:40:43 --> 00:40:46

In newspapers, at that time social media was

00:40:46 --> 00:40:48

not so common, newspapers were more prevalent.

00:40:49 --> 00:40:51

In all this, they started promoting it that

00:40:51 --> 00:40:54

imagine being allergic to people, how it feels

00:40:54 --> 00:40:57

to you, imagine you go somewhere and you

00:40:57 --> 00:40:59

cannot talk to people.

00:40:59 --> 00:41:01

So you have got this social phobia and

00:41:01 --> 00:41:03

we have the solution for you.

00:41:03 --> 00:41:06

So normally, those who had a little anxiety

00:41:06 --> 00:41:08

to go in front of people, they labeled

00:41:08 --> 00:41:10

themselves as social phobia.

00:41:10 --> 00:41:13

And the research says, after this campaign, the

00:41:13 --> 00:41:18

rare disease of social phobia became the most

00:41:18 --> 00:41:20

common disease of that century.

00:41:21 --> 00:41:23

You can see the effect of this.

00:41:23 --> 00:41:27

A very common example which I think we

00:41:27 --> 00:41:29

should discuss is of cosmetics.

00:41:29 --> 00:41:30

Cosmetic problems.

00:41:31 --> 00:41:33

There is a very good scientific evidence in

00:41:33 --> 00:41:35

this that it is baldness.

00:41:37 --> 00:41:42

Now, in this era of hair transplant surgeries

00:41:42 --> 00:41:45

and advances in hair transplant, baldness is a

00:41:45 --> 00:41:48

very stigmatized kind of and it's a disease.

00:41:48 --> 00:41:49

Now it's a disease.

00:41:50 --> 00:41:54

Before the introduction of the treatment for baldness,

00:41:54 --> 00:41:55

it was not a disease.

00:41:56 --> 00:41:59

It was a common aging process which was

00:41:59 --> 00:42:02

usually expected in an age time frame.

00:42:03 --> 00:42:06

You expected that your hair would fall, some

00:42:06 --> 00:42:09

people's hair would fall and this baldness would

00:42:09 --> 00:42:09

come.

00:42:10 --> 00:42:14

But pharmaceutical company made a drug called Minoxidil.

00:42:15 --> 00:42:18

And they actually made it to control blood

00:42:18 --> 00:42:18

pressure.

00:42:18 --> 00:42:24

But they saw that in side effect, hair

00:42:24 --> 00:42:25

growth in the body was increasing.

00:42:25 --> 00:42:29

So they introduced this medicine as a treatment

00:42:29 --> 00:42:30

for baldness.

00:42:30 --> 00:42:31

Now, baldness was not a disease.

00:42:31 --> 00:42:32

People did not want to take it.

00:42:33 --> 00:42:36

To make it a disease, they wrote papers

00:42:36 --> 00:42:37

on it.

00:42:37 --> 00:42:41

They were pharmaceutically funded papers which were written

00:42:41 --> 00:42:43

by medical experts.

00:42:44 --> 00:42:50

And they were published They linked that people

00:42:50 --> 00:42:53

who have baldness, their job prospects are very

00:42:53 --> 00:42:58

less, their emotional health suffers a lot, their

00:42:58 --> 00:42:59

relationships suffer a lot.

00:43:00 --> 00:43:00

All sorts of things.

00:43:01 --> 00:43:04

Now, the person who never thought that all

00:43:04 --> 00:43:07

this is happening because of my baldness, ultimately

00:43:07 --> 00:43:09

he started linking all of this to that

00:43:09 --> 00:43:10

baldness.

00:43:10 --> 00:43:11

And it became a disease.

00:43:12 --> 00:43:14

Initially, there was a treatment Minoxidil.

00:43:14 --> 00:43:17

Now, there are a lot of advances in

00:43:17 --> 00:43:19

hair transplant surgeries.

00:43:19 --> 00:43:22

And from there, all the cosmetic surgeries, anti

00:43:22 --> 00:43:25

-aging treatments, whitening treatments, if you go into

00:43:25 --> 00:43:28

the history, you will find that it was

00:43:28 --> 00:43:29

not a disease.

00:43:29 --> 00:43:32

It was a normal human phenomenon to make

00:43:32 --> 00:43:33

it a disease.

00:43:34 --> 00:43:36

How much work did the farmers do?

00:43:37 --> 00:43:39

How many journals did they fund?

00:43:39 --> 00:43:42

And nowadays, the biggest thing is social media.

00:43:42 --> 00:43:44

What was not funded on social media?

00:43:45 --> 00:43:46

And then that disease was introduced.

00:43:47 --> 00:43:49

So now the big question is that the

00:43:49 --> 00:43:51

disease you think of is actually a disease

00:43:51 --> 00:43:51

or not?

00:43:52 --> 00:43:53

And where is the concept of the disease

00:43:53 --> 00:43:54

coming from?

00:43:54 --> 00:43:56

Is that a medical evidence?

00:43:56 --> 00:43:59

Or is it the result of pharmaceutically funded

00:43:59 --> 00:44:02

advertisements that it is becoming a disease?

00:44:02 --> 00:44:04

So I have a lot of examples, but

00:44:04 --> 00:44:06

I don't have time to explain them all.

00:44:06 --> 00:44:10

But this thing is really serious.

00:44:10 --> 00:44:18

When we are medicalizing then obviously the anxiety

00:44:18 --> 00:44:21

we are trying to tackle is increasing.

00:44:22 --> 00:44:24

Thank you for sharing that, Dr. Urooj.

00:44:26 --> 00:44:32

Again, it's not far-fetched to imagine that

00:44:32 --> 00:44:34

if these are trends, if this is how

00:44:34 --> 00:44:39

they have operated in the past, it may

00:44:39 --> 00:44:40

well be that when there is a surge

00:44:40 --> 00:44:43

in optimization, they go and ask Google what

00:44:43 --> 00:44:45

problems people search for the most.

00:44:45 --> 00:44:47

If they go and see that problem, what

00:44:47 --> 00:44:50

are the most searched topics, and develop a

00:44:50 --> 00:44:56

good diagnostic label for it, make a medicine

00:44:56 --> 00:45:00

for it, popularize that label, and when people

00:45:00 --> 00:45:04

have to ask Dr. Google, those who have

00:45:04 --> 00:45:07

10% of the symptoms, after reading that

00:45:07 --> 00:45:12

article or that blog post, they will become

00:45:12 --> 00:45:13

30-40%.

00:45:13 --> 00:45:16

If there is anxiety about that, they will

00:45:16 --> 00:45:17

become 40-50%.

00:45:17 --> 00:45:19

That's what anxiety does.

00:45:22 --> 00:45:23

The Google Syndrome.

00:45:23 --> 00:45:25

I have a medicalization of a model.

00:45:25 --> 00:45:27

It's called the Google Syndrome.

00:45:28 --> 00:45:28

Exactly.

00:45:30 --> 00:45:33

And that happens precisely because you're on Google

00:45:33 --> 00:45:35

and you're looking for diagnostic labels and you

00:45:35 --> 00:45:38

think that there is a pill that can

00:45:38 --> 00:45:40

solve all your problems and all your issues,

00:45:40 --> 00:45:42

and that's not how life works.

00:45:43 --> 00:45:44

Oh God.

00:45:44 --> 00:45:46

You will also get evidence for this.

00:45:47 --> 00:45:50

Normally, when medicines are very expensive, you ask

00:45:50 --> 00:45:52

why they are so expensive.

00:45:53 --> 00:45:56

The answer is that clinical trials require a

00:45:56 --> 00:45:56

lot of money.

00:45:57 --> 00:45:58

Research requires a lot of money.

00:45:58 --> 00:46:00

There is a lot of work behind making

00:46:00 --> 00:46:00

it.

00:46:01 --> 00:46:05

But when you see the actual figures, the

00:46:05 --> 00:46:08

clinical trials that they are spending, they are

00:46:08 --> 00:46:10

spending double on drug advertisement.

00:46:10 --> 00:46:13

All the ads that come out on TV

00:46:13 --> 00:46:16

and social media and all the other platforms.

00:46:17 --> 00:46:19

So why are they spending so much there?

00:46:19 --> 00:46:21

Because the sale they are making from there

00:46:21 --> 00:46:24

will not be made from such diseases until

00:46:24 --> 00:46:26

they make it a disease and introduce it.

00:46:26 --> 00:46:28

The marketing budget is more.

00:46:28 --> 00:46:31

Actual research, real science budget is less.

00:46:32 --> 00:46:32

It is the most.

00:46:33 --> 00:46:34

Okay.

00:46:36 --> 00:46:39

May well be, we said that the decision

00:46:39 --> 00:46:41

on which disease is there and which is

00:46:41 --> 00:46:43

not should be done by a responsible board

00:46:43 --> 00:46:46

of doctors rather than by pharmaceutical companies.

00:46:46 --> 00:46:48

Pharmaceutical companies said, there is no problem, there

00:46:48 --> 00:46:49

are doctors in our board.

00:46:50 --> 00:46:52

There are doctors who work for us.

00:46:53 --> 00:46:55

And they did the research.

00:46:56 --> 00:46:58

But the name of the pharmaceutical company will

00:46:58 --> 00:46:59

not be of a pharmaceutical company, it will

00:46:59 --> 00:46:59

be of a doctor.

00:47:00 --> 00:47:02

So how long does it take for a

00:47:02 --> 00:47:02

doctor to sell?

00:47:04 --> 00:47:05

Alright.

00:47:05 --> 00:47:07

So the budget on marketing is more.

00:47:09 --> 00:47:13

So the medicines that we buy, in that

00:47:13 --> 00:47:15

we are also paying for their marketing.

00:47:16 --> 00:47:19

We are not paying for their intellectual investment

00:47:19 --> 00:47:22

or scientific investment.

00:47:23 --> 00:47:26

So, Dr. Asma, does that have anything to

00:47:26 --> 00:47:29

do with why there is a difference or

00:47:29 --> 00:47:32

so much of a difference in different kinds

00:47:32 --> 00:47:34

of medications that we find in the pharmacy?

00:47:35 --> 00:47:38

Some medicines are very cheap, some are very

00:47:38 --> 00:47:38

expensive.

00:47:39 --> 00:47:42

What is going on there?

00:47:46 --> 00:47:49

This cycle starts when the first medicine is

00:47:49 --> 00:47:49

made.

00:47:50 --> 00:47:52

The first of its kind medicine is made.

00:47:52 --> 00:47:54

The original brand, which we call innovative drug.

00:47:54 --> 00:47:58

So, if its price is more, then it

00:47:58 --> 00:48:01

is understandable because to make a drug from

00:48:01 --> 00:48:04

scratch, it takes up to 3 billion US

00:48:04 --> 00:48:05

dollars.

00:48:05 --> 00:48:06

It takes 10 to 15 years.

00:48:07 --> 00:48:09

Obviously, when it comes to the market, it

00:48:09 --> 00:48:11

has a patent, which is a period of

00:48:11 --> 00:48:13

exclusivity for 10 to 15 years.

00:48:13 --> 00:48:14

No one can copy it.

00:48:14 --> 00:48:16

Only they can sell it.

00:48:17 --> 00:48:20

They have to recover all their costs, save

00:48:20 --> 00:48:22

future profits, save future research and development.

00:48:23 --> 00:48:25

If they want investment, they recover all the

00:48:25 --> 00:48:25

costs.

00:48:27 --> 00:48:31

When their patent expires, the other pharmaceutical companies

00:48:31 --> 00:48:34

get this free hand to produce a simple

00:48:34 --> 00:48:36

copy-paste of the same formula.

00:48:36 --> 00:48:37

They don't do research, they sell the same

00:48:37 --> 00:48:40

formula under their name.

00:48:42 --> 00:48:46

When they sell it, in foreign countries, it

00:48:46 --> 00:48:47

is known as generic.

00:48:49 --> 00:48:51

You have a branded drug and a generic

00:48:51 --> 00:48:51

drug.

00:48:52 --> 00:48:55

In Pakistan, the situation is different.

00:48:55 --> 00:48:58

There is a generic brand and a branded

00:48:58 --> 00:48:58

generic.

00:49:02 --> 00:49:05

Here, there is a cost difference.

00:49:06 --> 00:49:08

The cost difference is not 5 to 10

00:49:08 --> 00:49:09

rupees.

00:49:09 --> 00:49:10

It is in hundreds.

00:49:12 --> 00:49:15

If you keep a medicine for 5 to

00:49:15 --> 00:49:18

10 days, it is not a profit margin.

00:49:18 --> 00:49:21

But if there is a drug that is

00:49:21 --> 00:49:24

used on a daily basis, like cholesterol lowering

00:49:24 --> 00:49:30

drugs, antihypertensives, their cost is anti-depressants.

00:49:30 --> 00:49:36

The price difference from 20 to 200 rupees

00:49:36 --> 00:49:38

becomes very extreme.

00:49:39 --> 00:49:41

Why is there a price difference?

00:49:42 --> 00:49:43

They are not doing research.

00:49:44 --> 00:49:45

Why are they charging so much?

00:49:45 --> 00:49:49

There are many factors.

00:49:49 --> 00:49:54

The biggest factor is that this is not

00:49:54 --> 00:49:57

our attempt to chastise anyone.

00:49:57 --> 00:49:59

This is to tell you that there are

00:49:59 --> 00:50:02

many factors that influence the final price.

00:50:04 --> 00:50:07

First off, there are poor policies by the

00:50:07 --> 00:50:08

Drug Regulation Authority.

00:50:09 --> 00:50:12

There is no comparative cost analysis.

00:50:12 --> 00:50:14

If one company is selling at this price,

00:50:15 --> 00:50:17

the generic of the same drug should be

00:50:17 --> 00:50:18

sold at the same price.

00:50:19 --> 00:50:23

The principle of generic is that you have

00:50:23 --> 00:50:26

to prove to the Drug Regulation Authority that

00:50:26 --> 00:50:28

the drug that we have copied and pasted

00:50:28 --> 00:50:33

is as safe and effective as your innovator

00:50:33 --> 00:50:33

drug.

00:50:34 --> 00:50:38

But over here, we are registering medicine on

00:50:38 --> 00:50:41

medicine but we are not asking them to

00:50:41 --> 00:50:42

prove the same.

00:50:43 --> 00:50:46

The only problem is not the price difference.

00:50:46 --> 00:50:48

If a person is getting an effective medicine,

00:50:49 --> 00:50:50

he can pay more.

00:50:51 --> 00:50:53

Some people can pay more.

00:50:54 --> 00:50:56

The problem here is that it becomes double

00:50:56 --> 00:50:59

or triple and becomes more severe because people

00:50:59 --> 00:51:03

are paying and there is no guarantee that

00:51:03 --> 00:51:06

the generic medicine they are using is really

00:51:06 --> 00:51:08

effective or not.

00:51:08 --> 00:51:10

I don't think anyone of us has ever

00:51:10 --> 00:51:15

said in our practice that we have done

00:51:15 --> 00:51:16

a course on the medicine you are giving

00:51:16 --> 00:51:17

us and we did not find any difference.

00:51:20 --> 00:51:26

First of all, our Drug Regulating Authorities do

00:51:26 --> 00:51:27

not have any check and balance on this.

00:51:28 --> 00:51:33

Secondly, this country is making generic medicine but

00:51:33 --> 00:51:35

our raw materials are coming from India and

00:51:35 --> 00:51:36

China.

00:51:36 --> 00:51:40

Because of that import, our cost increases.

00:51:41 --> 00:51:45

In Pakistan, we have another hobby which is

00:51:45 --> 00:51:46

to create artificial drugs.

00:51:49 --> 00:51:53

When we do that, let's say during the

00:51:53 --> 00:51:59

time of infections, I remember in our wars,

00:51:59 --> 00:52:03

vancomycin and tezobectamin were always short.

00:52:04 --> 00:52:06

They were not available in hospitals.

00:52:07 --> 00:52:10

We had to prescribe to people and they

00:52:10 --> 00:52:11

used to bring it from outside.

00:52:12 --> 00:52:15

The artificial drugs are not available in hospitals

00:52:15 --> 00:52:19

and because of that the pharmaceutical companies sell

00:52:19 --> 00:52:23

it from outside and the price increases further.

00:52:25 --> 00:52:27

Where will you stop and where will you

00:52:27 --> 00:52:28

check and balance?

00:52:29 --> 00:52:34

If we talk about the pharmaceutical companies themselves,

00:52:35 --> 00:52:37

they have to produce the same drug which

00:52:37 --> 00:52:39

is beneficial for them.

00:52:39 --> 00:52:44

If they produce simple folic acid then the

00:52:44 --> 00:52:45

cost is very low.

00:52:46 --> 00:52:48

But if they combine the same folic acid

00:52:48 --> 00:52:53

with other multivitamins and we see a lot

00:52:53 --> 00:52:59

of multivitamins in a bottle this is your

00:52:59 --> 00:53:00

one-stop shop.

00:53:01 --> 00:53:06

There the cost of producing those drugs is

00:53:06 --> 00:53:08

high and the earning is high.

00:53:10 --> 00:53:13

The spider web is such that you don't

00:53:13 --> 00:53:16

know where to start and the things are

00:53:16 --> 00:53:17

going to start getting streamlined.

00:53:19 --> 00:53:22

The marketing costs add on.

00:53:23 --> 00:53:26

Marketing is not direct to the consumer but

00:53:26 --> 00:53:33

to the doctors and pharmaceutical representatives and pharmacies.

00:53:33 --> 00:53:39

In that the more a doctor prescribes a

00:53:39 --> 00:53:43

medicine at the end of the day he

00:53:43 --> 00:53:46

can claim his share from that pharmaceutical company

00:53:46 --> 00:53:47

that I have given you so much medicine.

00:53:48 --> 00:53:51

Now this is my share.

00:53:52 --> 00:53:56

Then your polypharmacy the more medicines you add

00:53:57 --> 00:53:59

the higher the cost increases.

00:54:01 --> 00:54:04

When I was doing this I was looking

00:54:04 --> 00:54:10

for a stop a check-in balance which

00:54:10 --> 00:54:11

was nowhere.

00:54:12 --> 00:54:15

Now I don't have a guarantee that this

00:54:15 --> 00:54:17

medicine is effective nor do I have a

00:54:17 --> 00:54:21

guarantee that this generic medicine is safe or

00:54:21 --> 00:54:21

not.

00:54:23 --> 00:54:24

I am totally blind.

00:54:24 --> 00:54:25

I am a doctor and I am blind.

00:54:26 --> 00:54:30

I don't know that a patient comes to

00:54:30 --> 00:54:31

me in the OPD and this happens countless

00:54:31 --> 00:54:34

times in our households that you prescribe a

00:54:34 --> 00:54:37

medicine and they would be like you prescribe

00:54:37 --> 00:54:42

the medicine and they would be like you

00:54:42 --> 00:54:50

prescribe the medicine and they would be like

00:54:50 --> 00:54:50

and they would be like you prescribe the

00:54:50 --> 00:54:58

medicine and they would be like you prescribe

00:54:58 --> 00:55:01

the medicine and they would be like you

00:55:01 --> 00:55:04

prescribe the medicine and they would be like

00:55:04 --> 00:55:12

you prescribe the medicine Okay Dr. Asma, please

00:55:40 --> 00:55:41

I don't know if it's safe or effective.

00:55:44 --> 00:55:47

But I cannot do that.

00:55:49 --> 00:55:51

And this is where we stand as as

00:55:51 --> 00:55:51

specialists.

00:55:52 --> 00:55:55

We can well imagine the lay person, the

00:55:55 --> 00:55:56

common man.

00:55:58 --> 00:56:00

I guess ignorance is bliss.

00:56:05 --> 00:56:08

generics and we we don't have a lot

00:56:08 --> 00:56:11

of time but we also have this understanding.

00:56:41 --> 00:56:46

And apparently that is a setup that India

00:56:46 --> 00:56:49

does have or is developing or has developed

00:56:49 --> 00:56:50

to some extent.

00:56:51 --> 00:56:54

And even the concept of it is very

00:56:54 --> 00:56:56

novel or very new.

00:56:59 --> 00:57:03

We are we do hear of some people

00:57:03 --> 00:57:07

making some inroads of efforts to get that

00:57:07 --> 00:57:09

regulation started or start making those efforts.

00:57:16 --> 00:57:20

To find out more about that.

00:57:24 --> 00:57:27

Direct to consumer marketing and then there's the

00:57:27 --> 00:57:29

to doctor marketing.

00:57:39 --> 00:57:46

It's introduction.

00:57:50 --> 00:57:58

marketing or promotion incentives

00:57:58 --> 00:58:04

if they prescribe a specific medicine.

00:58:12 --> 00:58:16

It's complicated.

00:58:16 --> 00:58:26

doctors incentives incentives

00:58:26 --> 00:58:35

the majority of the doctors said conferences

00:58:35 --> 00:58:48

or educational activities pharmaceutical incentives proper

00:58:48 --> 00:58:53

gifts So, who are you going to hospital?

00:58:55 --> 00:59:02

watches up to cars foreign trips and cars

00:59:02 --> 00:59:10

brand reminders inconsequential

00:59:10 --> 00:59:20

and it goes

00:59:20 --> 00:59:29

to your sponsored trips doctors educational conferences pharmaceutical

00:59:34 --> 00:59:50

polypharmacy there's

00:59:50 --> 01:00:00

so much more to discuss or or

01:00:03 --> 01:00:05

one thing that all of our audience will

01:00:05 --> 01:00:11

have noticed is that my entire panel and

01:00:11 --> 01:00:15

me we're fairly on the younger side of

01:00:15 --> 01:00:18

the line all of you are in your

01:00:18 --> 01:00:25

20s I'm in my early 30s and this

01:00:25 --> 01:00:30

is actually representative of a trend the longer

01:00:30 --> 01:00:34

you are in this field the more desensitized

01:00:34 --> 01:00:38

you become to these problems I will be

01:00:38 --> 01:00:45

hard pressed to find three professors to sit

01:00:45 --> 01:00:46

with me and have this conversation.

01:00:48 --> 01:00:49

I'm not saying they're not there.

01:00:49 --> 01:00:51

I'm just saying it'll be very hard for

01:00:51 --> 01:00:54

me to bring them together and have this

01:00:54 --> 01:00:56

kind of a conversation and have them share

01:00:56 --> 01:01:00

this kind of information with you the few

01:01:00 --> 01:01:02

people that I will be able to get

01:01:02 --> 01:01:04

in touch with I hope we will be

01:01:04 --> 01:01:07

able to have a psych with them as

01:01:07 --> 01:01:07

well.

01:01:15 --> 01:01:21

This is these are deep-seated problems these

01:01:21 --> 01:01:24

are deep-seated problems and we want something

01:01:24 --> 01:01:28

done we want to do something we want

01:01:28 --> 01:01:31

there to be what that something is we'll

01:01:31 --> 01:01:34

be very honest we don't have the first

01:01:34 --> 01:01:48

clue these spiderwebs we

01:01:48 --> 01:01:52

present not only what we have gathered but

01:01:52 --> 01:01:55

where we fall short and we fall drastically

01:01:55 --> 01:01:59

short so we continue raising awareness talking about

01:01:59 --> 01:02:08

all of these issues talking about we've only

01:02:08 --> 01:02:12

touched we've only scratched the surface here right

01:02:12 --> 01:02:14

this is just the tip of the iceberg

01:02:17 --> 01:02:34

definitely I

01:02:34 --> 01:02:40

don't want to okay thank you all for

01:02:40 --> 01:02:43

being here thank you all for watching we've

01:02:43 --> 01:02:45

done what we could and we will look

01:02:45 --> 01:02:47

to do more but this is where we

01:02:47 --> 01:02:50

ask you to help propagate this so that

01:02:50 --> 01:02:53

it shakes the right corridors it creates the

01:02:53 --> 01:02:55

ripples where it needs to create the ripples

01:02:55 --> 01:02:59

and people start feeling the intensity of the

01:02:59 --> 01:03:02

situation for what it really is don't wait

01:03:02 --> 01:03:05

for an incident even though those incidents are

01:03:05 --> 01:03:12

happening just me people are dying as a

01:03:12 --> 01:03:14

consequence of what this corruption is talking about

01:03:14 --> 01:03:16

do you want me to get more explicit

01:03:16 --> 01:03:18

than that people are dying every day as

01:03:19 --> 01:03:22

a result of the problems that we spoke

01:03:22 --> 01:03:26

about without any exaggeration and there is no

01:03:26 --> 01:03:29

data give a kid man they can we

01:03:29 --> 01:03:31

say we can say categorically give a boss

01:03:33 --> 01:03:36

so it is literally a matter of life

01:03:36 --> 01:03:38

and death and so we take it up

01:03:38 --> 01:03:41

thank you all for watching we will be

01:03:41 --> 01:03:42

seeing you around there's a lot of material

01:03:42 --> 01:03:45

that we're sharing from our telepsychiatry pages on

01:03:45 --> 01:03:47

our social media related to all of what

01:03:47 --> 01:03:50

we touched upon to see if we can

01:03:50 --> 01:04:00

water down simplify understand thank you all

01:04:00 --> 01:04:02

for supporting us in this

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